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Research Interests
Structure-function relationships of the biologically active microbial polysaccharides. Physico-chemical characterization and modification of fungal and bacterial polysaccharides. Application of polysaccharides in biology, medicine, agriculture, food industry, etc.
Selected Publications (full list available on request)
(1→3,1→6)-β-D-Glucans of yeasts and fungi and their biological activity.
Kogan, G. In: Studies in Natural Products Chemistry (Ed. Atta-ur-Rahman) Vol. 23 Bioactive Natural Products (Part D), Elsevier, Amsterdam, Lausanne, New York, Oxford, Shannon, Singapore, Tokyo (2000) ISBN 0-444-50606-3, pp. 107-152. Increased efficiency of Lewis lung carcinoma chemotherapy with a macrophagstimulator-yeast carboxymethyl glucan.
G. Kogan, J. Šandula, T. A. Korolenko, O. V. Falameeva, O. N. Poteryaeva, S. Ya. Zhanaeva, O. A. Levina, T. G. Filatova, V. I. Kaledin International Immunopharmacology 2 (2002) 775-781. Human monocyte scavenger receptors are pattern recognition receptors for (1→3)-β-D-glucans.
P.J. Rice, J.L. Kelley, G. Kogan, H.E. Ensley, J.H. Kalbfleisch, I.W. Browder, D.L. Williams Journal of Leukocyte Biology 72 (2002) 140-146. Conjugation of meningococcal lipooligosaccharides through their lipid A terminus conserves their inner epitopes and results in conjugate vaccines having improved immunological properties.
M. Mieszala, G. Kogan, H. J. Jennings Carbohydrate Research 338 (2003) 167-175. Regulation of activity of cathepsins B, L, and D in murine lymphosarcoma model at a combined treatment with cyclophosphamide and yeast polysaccharide.
T. A. Khalikova, S. Ya. Zhanaeva, T. A. Korolenko, V. I. Kaledin, G. Kogan Cancer Lett., 223 (2005) 77-83. Antioxidant properties of yeast (1→3)-β-D-glucan studied by Electron Paramagnetic Resonance spectroscopy and its activity in the adjuvant arthritis.
G. Kogan, A. Staško, K. Bauerová, M. Polovka, L. Šoltés, V. Brezová, J. Navarová, D. Mihalová Carbohydr. Polym., 61 (2005) 18-28. Degradative action of reactive oxygen species on hyaluronan.
L. Šoltés, R. Mendichi, G. Kogan, J. Schiller, M. Stankovská, J. Arnhold Biomacromolecules, 7 (3) (2006) 659-668. Carbohydrate-containing components of biofilms produced in vitro by some staphylococcal strains related to orthopaedic prosthesis infection.
I. Sadovskaya, P. Chaignon, G. Kogan, A. Chokr, E. Vinogradov, S. Jabbouri FEMS Immunol. Med. Microbiol. 47 (2006) 75-82. Diverse biomodulatory effects of glucomannan from Candida utilis.
E. Miadoková, S. Svidová, V. Vlčková, V. Dúhová, S. Naďová, P. Rauko, G. Kogan Toxicology in Vitro 20 (2006) 649-657. |