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PhD study
  • Synthesis of glycosylmethylated and hydroxylated nitrogen heterocycles as possible inhibitors of enzymes catalysing conversion of sugars.
  • Supervisor: Marek Baráth, PhD

  • Modified glycan interfaces and their applications.
  • PhD student: Filip Květoň, MSc

  • Regulatory mechanisms of the mitochondrial phospholipid cardiolipin formation in the yeasts Saccharomyces cerevisiae
  • PhD student: Lucia Pokorná, MSc
    Supervisor: Peter Griač, PhD

  • Analysis of complex carbohydrates by biosensors.

  • Antimicrobial substances of honeybee larval jelly: the investigation of their contents in jellies in bee colonies and the efficiency against pathogens of bee brood.
  • PhD student: Maroš Laho, MSc

  • Synthesis, characterization and properties of potential inhibitors of glycosyltransferases.

  • Mass spectrometry of flavours and fragrances.

  • Characterization of new genes essential for correct meiotic segregation of chromosomes in yeast Schizosaccharamyces pombe.
  • PhD student: Ivana Mišová, MSc
    Supervisor: Peter Griač, PhD

  • Phospholipids and their influence on morphology and function of mitochondria.
  • Supervisor: Peter Griač, PhD

  • Multiparameter characterization of a new generation of immobilized biocatalysts.
  • Supervisor: Marek Bučko, PhD

  • Study of the glycosylation changes of proteins as potential biomarkers using biochips.

  • Chemoenzymatic synthesis of bioactive glycophenolics.
  • PhD student: Peter Kis, MSc

  • Synthetic glycoconjugates for various medicinal chemistry studies.
  • PhD student: Tomáš Klunda, MSc

  • Biopolymers of microalgae, structure and properties.
  • PhD student: Michal Halaj, MSc
    Supervisor: Peter Capek, PhD

  • Lipid droplets as multifunctional organelles of eukaryotic cells.
  • PhD student: Zsófia Csáky, MSc
    Supervisor: Ivan Hapala, PhD

  • Regulatory mechanisms of lipid homeostasis in the yeast Saccharomyces cerevisiae.
  • Supervisor: Peter Griač, PhD

  • Label-free electrochemical glycoprofiling of prostate cancer biomarkers.

  • Glyco-recognition by microarray and SPR biochips.

  • Enzymes required for plant hemicellulose utilization.

  • Cell mechanism of sterols.
  • PhD student: Marek Pápay, MSc

  • Preparation, characterization and applications of lectin devices in cancer diagnosis.

  • Synthetic potential of glycosidases.


  • 2016
  • Preparation and utilization of glycan biochips.

  • Application of nanotechnologies in preparation of lectin biosensors.

  • Inhibition of the cell wall formation in yeast.

  • Study of relation between structure and function of glycoconjugates in living systems.
  • Supervisor: Ján Mucha, PhD

    2015
  • Study of immunity responce induced by surface saccharides of microbial pathogens.

  • Investigation of biomolecular factors of the defense of honeybee colonies against microbial pathogens.

  • Expression and biochemical characterization of selected glycoenzymes.

  • Enzymatic acylations of saccharides.
  • PhD student: Andrej Chyba, MSc

  • Biochips and biosensors based on lectin biorecognition.

  • Regulatory mechanisms of lipid homeostasis in the yeast Saccharomyces cerevisiae.
  • PhD student: Peter Seč, MSc
    Supervisor: Peter Griač, PhD

  • Development of new high performance technique for the encapsulation of biocatalysts for production of aromas.
  • Supervisor: Marek Bučko, PhD

    2014
  • The role of apiculate microflora in vineyard ecosystem and winemaking.

  • Expression and biochemical characterization of selected bioenergetic enzymes.
  • Supervisor: Jozef Nahalka, PhD

  • Vibrio cholerae antigens. Preparation and immunogenicity of glycoconjugates.

  • Preparation of nanostructured interfaces and their use in biorecognition.

  • Structure-function relationship of plant transglycosylases.

  • Immunobiological characteristiques of polysaccharidic antigens of pathogenic Candida spp.

  • 2013
  • Production of antimicrobial peptides in honeybee colonies.

  • Úloha kvasinkového fosfatidylinozitol transferového proteínu a jeho homológov vo fyziológii eaukaryotickej bunky.
  • Supervisor: Peter Griač, PhD

  • Molekulárne mechanizmy kontroly biogenézy neutrálnych lipidov u kvasiniek.
  • Supervisor: Ivan Hapala, PhD

  • Construction and application of enzymatic and microbial biofuel cells (biobaterries) using nanotechnological tools.
  • PhD student: Jaroslav Filip, PhD

  • Diversity of yeasts inhibiting the plant material with emphasis on their characteristics and activity.

  • Genetically engineered microorganisms as whole-cell catalysts for enantioselective biooxidations by novel immobilization biotechnologies.

  • Role of the lipid transfer proteins in metabolism of eukaryotic cell.
  • Supervisor: Peter Griač, PhD

    2012
  • Study of the affinity interactions of biomolecules on the solid support by quartz crystal microbalance.

  • 2011
  • NMR study of metabolism of bacteria isolated from clouds water: their role in chemistry of the atmosphere.
  • Supervisor: Anne Marie Delort, PhD (University Blaise Pascal, Clermont Ferrand, France)

  • Molecular modeling of catalytic mechanism of glycosyltransferases and design of their inhibitors.
  • PhD student: Michal Raab, PhD

  • Biological and immunological characterization of antigen dominant mannoproteins of pathogen yeasts Candida; their utilization for preparation of subcellular vaccines.

  • Newly emerging pathogens - vibrios. Study of virulence and possible active immunomodulative prevention.
  • PhD student: Jana Korcová, PhD

    2010
  • Molecular modeling of the transition state structure of catalytic reactions.

  • Microbial esterases of wooddestroying fungi Phanerochaete chrysosporium.

  • Regulation of capsule formation in the yeast Cryptococcus.

  • 2009
  • Novel assay methods for transglycosylases.
  • PhD student: Ondřej Kosík, PhD

  • Preparation and immunological properties of mannan-protein conjugates of potential pathogenic Candida and Malassezia species.
  • Supervisor: Eva Machová, PhD

  • New flow biosensor systems with amperometric and calorimetric detection for fermentation and biotransformation monitoring.

  • Structure - function study of Arabidopsis thaliana core α 1,3-fucosyltransferase (FucTA).
  • PhD student: Peter Both, PhD
    Supervisor: Ján Mucha, PhD

  • Isolation and characterization of plant transglycosylases.

  • Synthesis of glycofuranosyl and glycopyranosyl C-nucleosides and their analogs.
  • PhD student: Michal Vojtech, PhD

  • Preparation and structural characterization of bioactive and other functional polysaccharides from economically important agricultural plants.

  • 2008
  • Immobilized biosystems: Potential and limitations of encapsulation of biocatalysts in polymer microcapsules.
  • PhD student: Marek Bučko, PhD

  • The role of transglutaminase in biosynthesis fungal cell walls.

  • Synthesis and characterization of neoglycoconjugates based on LPS of Vibrio cholerae 01.

  • Hyaluronic acid derivatives with biological properties.

  • 2007
  • Regulation of xylogenesis in vitro - effect of GGMOs on tracheary elements differentiation.

  • Microbial esterases of wooddestroying fungi Schizophylum commune.

  • The influence of chemical and physical factors on the yeast microflora in winery large production.

  • Reaction mechanism of glycosyltransferases.

  • Identification and some aspects of expression of larval nutrition antimicrobial peptide - royalisine in various colonies of honeybees Apis mellifera L.

  • Utilization of MALDI and ESI-MS techniques in the study of biomolecules.

  • 2006
  • Preparation, chemical and immunological characterization of glycoconjugates based on polysaccharidic surface antigens from the yeasts of Candida genus as potential vaccines.

  • Conidiation of Trichoderma fungi and its utilization in the culture plants protection.

  • Preparation of mimetics of lipide A.

  • Assay methods and isolation of xyloglucan endotransglycosylase (XET) isoforms from nasturtium (Tropaeolum majus) seeds.

  • 2005
  • Xylanolytic system of Schizophyllum communae.

  • Synthesis of anhydronitroalditol-based C-glycosylating agents.

  • Synthesis and characterization of aminoderivatives of saccharides structurally related to mannojirimycin.

  • Use of lignin in polymer blends.

  • 2003
  • Mechanism of reaction catalyzed by xyloglucan endotransglycosylase (XET).

  • Biophysical study of hyaluronan structure and pahtological processes in cartilage and brain using nuclear magnetic resonance.

  • Mrjp gene family of honeybee (Apis mellifera L.): computer analysis of putative mrjp promoters and genomic structure of mrjp1 gene coding for the most abundant protein of royal jelly.

  • Synthesis of bioactive proteins of larval nutrition of honey bees by heterologous expression.

  • 2002
  • Synthesis of glycoproteins. Preparation, characterization and their interaction with concanavalin A.

  • Isolation, characterization and function of lectin from Pinus nigra ARN.

  • Isolation and characterization of biologically active proteins and antimicrobial peptides of honeybee royal jelly.

  • 2001
  • Synthesis and properties of model compounds for ester type of lignin-carbohydrate linkage.
  • Supervisor: Dušan Joniak, PhD

  • Photoinduced conidiation in the fungus Trichoderma viride.

  • Plant β-mannans and their enzymatic degradation.

  • Biosynthesis of galactosylated glycoproteins in the yeast Cryptococcus laurentii.

  • 1999
  • Annulated derivatives of purine-2,6-diones.
  • Supervisor: Alfonz Rybár, PhD

  • Synthesis of C-glycosyl analogues of biologically significant saccharides.

  • Biotechnological use of plant cell biomass for production of secondary metabolites.

  • Mutual isomerization of 2-ketoses and 2-C-(hydroxymethyl)aldoses catalyzed by molybdic acid.

  • Isolation and biochemical characterization of a GTP-ase-activating protein specific for members of Ypt/Rab family of small GTP-ases.

  • 1998
  • Chemical ionization mass spectrometry of saccharides.

  • Characterization of immobilized biocatalysts using flow microcalorimetry.

  • β-Mannanolytic system of Aureobasidium pullulans.

  • Institute of Chemistry
    Slovak Academy of Sciences
    webmaster@chem.sk
    2016