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Research projects
Projects of the Scientific Grant Agency (VEGA)
Glycosylhydrolases of secretion pathway of model organism: cloning, expression, purification and characterisation of multigenic family of mannosidases from D. melanogaster
Principal investigator: Ján Mucha, PhD (01/2008-12/2010)
Regulation of shed of cryptococal capsular polysaccharide
Principal investigator: Nadežda Kolarova, PhD (01/2008-12/2010)
Catalytic mechanism of glycosyltransferases; design and synthesis of their inhibitors
Principal investigator: Ján Hirsch, PhD, DSc (01/2008-12/2010)
Biological activity of native and modified polysaccharides from medicinal plants.
Principal investigator: Peter Capek, PhD (01/2008-12/2010)
Study of structure of biologically active saccharides and their intermolecular complexes using methods of NMR spectroscopy and theoretical chemistry
Principal investigator: Miloš Hricovíni, PhD (01/2008-12/2010)
Biosurfactants from saccharides
Principal investigator: Vladimír Mastihuba, PhD (01/2008-12/2010)
Study of the expression of antibacterial peptides-defensins in honeybee colonies
Principal investigator: Jaroslav Klaudiny, PhD (01/2009-12/2011)
Synthesis of the long-chain macrocyclic polyanhydroalditols
Principal investigator: Assoc. Prof. Ladislav Petruš, PhD, DSc (01/2009-12/2011)
Transglycosylases, their characterization and function in the formation and modification of plant and fungal cell walls
Principal investigator: Assoc. Prof. Vladimír Farkaš, PhD, DSc (01/2009-12/2011)
Structure-based design, synthesis and biological evaluation of anti-cancer agents with indolizidine core
Principal investigator: Juraj Kóňa, PhD (01/2009-12/2011)
Stimulation of conidiation by endogenous volatile compounds in Trichoderma
Principal investigator: Marek Nemčovič, PhD (01/2009-12/2011)
Natural and tailored hydrophobized polysaccharides with antioxidant and associative properties
Principal investigator: Zdenka Hromádková, PhD (01/2009-12/2012)
Glycomics - its potential for rapid characterization of microorganisms
Principal investigator: Vladimír Pätoprstý, PhD (01/2009-12/2012)
The creation, characteristics and reusing of acid mine drainage
Principal investigator (project leader from Min. Edu. SR): Assoc. Prof. Eva Michalková, PhD (01/2009-12/2011)
Principal investigator (deputy from IC SAS): Vladimír Pätoprstý, PhD
The utilization of plant polysaccharides in the therapy of cough
Principal investigator (project leader from Min. Edu. SR): Martina Šutovská, MD, PhD (01/2009-12/2011)
Principal investigator (deputy from IC SAS): Peter Capek, PhD
Microbial enzymes for bioconversion of plant hemicelluloses
Principal investigator: Peter Biely, PhD, DSc (01/2010-12/2013)
Ecology of yeasts inhabiting the fruit surfaces and flowers of fruit-trees with emphasis on the their characteristics, activity, and survival
Principal investigator: Elena Sláviková, PhD (01/2010-12/2013)
Chemical preparation characterization and immunological properties of conjugates based on selected oligosaccharide antigens of pathogenic Candida sp.
Principal investigator: Slavomír Bystrický, PhD, DSc (01/2010-12/2012)
Bioactive factor - galactoglucomannan - potential of a wood-related residue in the control of the plant development and protection
Principal investigator: Desana Lišková, PhD (01/2010-12/2013)
Deciphering the glycocode using tools of lectinomics: Nanoscale-controlled immobilisation of lectins with an microarray-based format of glycoform detection
Principal investigator: Peter Gemeiner, PhD, DSc (01/2010-12/2013)
Study of application of pathogen-host glycoprotein interactions in fight against the pathogen itself
Principal investigator: Jozef Nahálka, PhD (01/2010-12/2012)
NMR structural analysis of metabolites and other biologically active molecules
Principal investigator: Mária Matulová, PhD (01/2010-12/2012)
Projects of the Slovak Research and Development Assistance Agency (APVV, till 2005 APVT)
Microbial esterases cleaving linkages between saccharides and lignin in plant cell walls
Principal investigator: Peter Biely, PhD, DSc (03/2006-02/2009)
Genetically engineered microorganisms as whole-cell catalysts of
enantioselective biooxidations performing novel immobilization biotechnologies
Principal investigator: Peter Gemeiner, PhD, DSc (03/2006-02/2009)
Oligosaccharides, neoglyco-peptides/proteins and humanized plastics - their synthesis and applications
Principal investigator: Jozef Nahálka, PhD (03/2006-02/2009)
Synthesis and biological evaluation of some model compounds with potential antimycobacterial activity
Principal investigator: Monika Poláková, PhD (03/2006-02/2009)
Molecular mechanisms of action of new drugs interfering with oxidative stress - the important factor in etiopathogenesis of numerous diseases
Principal investigator: Assoc. Prof. Svorad Štolc, PhD, DSc (Institute of Experimental Farmacology SAS, 03/2006-02/2009)
Responsible investigator from IC SAS: Grigorij Kogan, PhD, DSc
Newly emerging pathogens - vibrios. Study of virulence and possible active immunomodulative prevention
Principal investigator: Slavomír Bystrický, PhD, DSc (01/2007-12/2010)
Computer modeling, synthesis and biological evaluation of selective inhibitors of Golgi mannosidase II
Principal investigator: Juraj Kóňa, PhD (01/2007-12/2010)
The study of antioxidant activity and adsorption affinity of lignin preparations isolated from wastes of plant biomass
Principal investigator: Prof. Božena Košíková, PhD, DSc (01/2007-12/2010)
Factors affecting uptake and transport of mineral elements in plants utilizable in phytotechnologies
Principal investigator: Prof. Alexander Lux, PhD (COST 2006 call, 01/2007-12/2010)
Immunostimulatory and antioxidant activities of plant polysaccharides - a relationship study
Principal investigator: Zdenka Hromádková, PhD (COST 2006 call, 01/2007-12/2010)
Transglycosylases of plant cell walls
Principal investigator: Assoc. Prof. Vladimír Farkaš, PhD, DSc (LPP 2006 call, 01/2007-12/2010)
Potential glycosylhydrolases inhibitors based on iminosugar derivatives
Principal investigator: Miroslav Koóš, PhD, DSc (09/2008-12/2010)
Protein motions and catalysis
Principal investigator: Igor Tvaroška, PhD, DSc (09/2008-12/2010)
New methodology of structural analysis of saccharides and glycoconjugates
Principal investigator: Vladimír Kováčik, PhD, DSc (09/2008-12/2010)
Projects of the State program of research and development
Program: Complex solution of support of research and development infrastructure utilization
Task: Upgrade of top nuclear magnetic resonance laboratory
Coordinator: Assoc. Prof. Tibor Liptaj, PhD
Principal investigator from IC SAS: Mária Matulová, PhD (2003-2010)
Projects of the Centres of Excellence of SAS
Centre Excellence for Biochemistry of Saccharides (GLYCOBIOS)
Principal investigator: Assoc. Prof. Vladimír Farkaš, PhD, DSc (01/01/2005-31/12/2008)
Centre of Advanced Computational Chemistry (COMCHEM))
Principal investigator from IAC SAS: Prof. Jozef Noga, PhD, DSc (01/01/2007-31/12/2010)
Principal investigator from IC SAS: Igor Tvaroška, PhD, DSc
Projects of the FP6 EU
GlycoGold: Exploration of nature and potential of Glyco-nano-particles (MRTN-CT-2004-005645)
Acronym: GLYCOGOLD
Principal coordinator: Prof. Johannis P. Kamerling (Netherland)
Principal investigator from IC SAS: Igor Tvaroška, PhD, DSc (04/2005-03/2009)
Functional genomics for biogenesis of plant cell walls (MRTN-CT-2004-512265)
Acronym: WALLNET
Principal coordinator: Prof. Henrik Vibe Scheller (Denmark)
Principal investigator from IC SAS: Assoc. Prof. Vladimír Farkaš, PhD, DSc (04/2005-03/2009)
(R)Evolutionary catalysis (MRTN-CT-2006-035866)
Acronym: REVCAT
Principal coordinator: Prof. Joost Nicolaas Hendrik Reek (Netherland)
Principal investigator from IC SAS: Igor Tvaroška, PhD, DSc (10/2006-09/2010)
Projects of the FP7 EU
Nanoparticles for therapy and diagnosis of Alzheimer disease (NMP4-LA-2008-212043)
Acronym: NAD
Principal coordinator: Prof. Massimo Masserini (Italy)
Principal investigator from IC SAS: Igor Tvaroška, PhD, DSc (09/2008-06/2013)
Enhancing access and services to East European users towards an efficient and
coordinated Pan-European pool of NMR capacities to anable global collaborative research & boost technological advancements (No. 228461)
Acronym: EAST-NMR
Principal coordinator: Prof. Harald Schwalbe (Germany)
Principal investigator from IC SAS: Miloš Hricovíni, PhD (02/2009-02/2012)
The other multilateral international projects
Biotechnology for lignocellulose biorefineries (COST Action FP0602)
Principal coordinator: Prof. Liisa Viikari (Finland)
Principal investigator from IC SAS: Peter Biely, PhD, DSc (02/2007-06/2011)
Bioencapsulation multiscale interaction analysis (COST Action 865)
Principal coordinator: Prof. Denis Poncelet (France)
Principal investigator from IC SAS: Peter Gemeiner, PhD, DSc (10/2005-01/2010)
Phytotechnologies to promote sustainable land use management and improve food safety (COST Action 859)
Principal coordinator: Dr Jean-Paul Schwitzguebel (Switzerland)
Principal investigator from IC SAS: Desana Lišková, PhD (05/2004-05/2009)
Control and exploitation of enzymes for added-value food products (COST Action 928)
Principal coordinator: Dr Johanna Buchert (Finland)
Principal investigator from IC SAS: Peter Biely, PhD, DSc (10/2005-01/2010)
Biotechnical functionalisation of renewable polymeric materials (COST Action 868)
Principal coordinator: Prof. Georg M. Guebitz (Austria)
Principal investigator from IC SAS: Peter Biely, PhD, DSc (05/2006-09/2010)
Multidisciplinary frontiers of magnetic resonance (ESF-Research Networking Programmes-PESC)
Acronym: EMAR
Principal coordinator: Prof. Miquel Pons (Spain)
Principal investigator from IC SAS: Mária Matulová, PhD (04/2007-04/2012)
Bilateral projects in the framework of interacademical and intergovernmental treaties about scientific and technological cooperation
NMR study of the metabolism of bacteria isolated from cloud water. Relation with chemistry of atmosphere (French-Slovak scientific and technological cooperation - program Štefánik)
Principal investigator: Mária Matulová, PhD (01/2008-12/2009)
Xylanolytic system of the xylose-fermenting yeast Pichia stipitis: Properties and engineering (APVV Call: Slovakia - South Africa 2007)
Principal investigator: Peter Biely, PhD, DSc (08/2008-12/2010)
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