About the Institute of Chemistry, SAS People at the Institute of Chemistry, SAS Research groups at the Institute of Chemistry, SAS Research at the Institute of Chemistry, SAS Products of the Institute of Chemistry, SAS

Senior Research Scientist
Department of Structure and Function of Saccharides, Head

Tel.: +421-2-59410323
Fax: +421-2-59410222
Research Interests
Analysis of structure and dynamics of saccharides in solution, structure of protein-carbohydrate complexes, molecular modelling of carbohydrates, analysis of NMR parameters.
Selected Papers
M. Hricovíni:
The effect of solvent and counterions upon structure and NMR spin-spin coupling constants in heparin disaccharide.
J. Phys. Chem. B 115 (2011) 1503-1511.
M. Hricovíni, F. Bízik:
Relationship between structure and three-bond proton-proton coupling constants in glycosaminoglycans.
Carbohydr. Res., 342 (2007) 779-783.
B3LYP/6-311++G** study of structure and spin-spin coupling constant in methyl 2-O-sulfo-α-L-iduronate.
Carbohydr. Res., 341 (2006) 2575-2580.
Structural Aspects of Carbohydrates and the Relations with their Biological Properties.
Current Medicinal Chemistry 11 (2004) 2565-2583.
M.Hricovíni, P. N. Nieto and G Torri:
NMR of Sulfated Oligo- and Polysaccharides.
In: NMR Spectroscopy of Glycoconjugates (J.Jimenez-Barbero and T.Peters, Eds.), Wiley-VCH, Weinheim, 2002, pp. 189-229.
M.Hricovíni, M.Guerrini, A. Bisio, G Torri, M. Petitou and B. Casu:
Conformation of heparin-derived pentasaccharide bound to antithrombin III.
Biochem. J., 359 (2001) 265-272.
M.Hricovíni, M.Guerrini and A. Bisio:
Structure of heparin-derived tetrasaccharide complexed to the plasma protein antithrombin derived from NOEs, J-couplings and chemical shifts.
Eur. J. Biochem., 261 (1999) 789-801.
M.Hricovíni, O.L.Malkina, F.Bízik, L.Turi-Nagy and V.G.Malkin:
Calculation of NMR Chemical Shifts and Spin-Spin Coupling Constants in the Monosaccharide Methyl-i-D-xylopyranoside Using a Density Functional Theory Approach.
J. Phys. Chem. A 101 (1997) 9756-9762.
M.Hricovíni and G.Torri:
Dynamics in Aqueous Solution of the Pentasaccharide Corresponding to the Binding Site of Heparin for Antithrombin III Studied by NMR Relaxation Measurements.
Carbohydr.Res., 268 (1995) 159-175.
M.Hricovíni, R.N.Shah and J.P.Carver:
Detection of Internal Motions in Oligosaccharides by 1H Relaxation Measurements at Different Magnetic Fields.
Biochemistry 31 (1992) 10018-10023.
Institute of Chemistry
Slovak Academy of Sciences