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Miloš HRICOVÍNI, PhD
Senior Research Scientist
Department of Structure and Function of Saccharides, Head

Tel.: +421-2-59410323
Fax: +421-2-59410222
Research Interests
Analysis of structure and dynamics of saccharides in solution, structure of protein-carbohydrate complexes, molecular modelling of carbohydrates, analysis of NMR parameters.
Selected Papers
M. Hricovíni:
The effect of solvent and counterions upon structure and NMR spin-spin coupling constants in heparin disaccharide.
J. Phys. Chem. B 115 (2011) 1503-1511.
M. Hricovíni, F. Bízik:
Relationship between structure and three-bond proton-proton coupling constants in glycosaminoglycans.
Carbohydr. Res., 342 (2007) 779-783.
M.Hricovíni:
B3LYP/6-311++G** study of structure and spin-spin coupling constant in methyl 2-O-sulfo-α-L-iduronate.
Carbohydr. Res., 341 (2006) 2575-2580.
M.Hricovíni:
Structural Aspects of Carbohydrates and the Relations with their Biological Properties.
Current Medicinal Chemistry 11 (2004) 2565-2583.
M.Hricovíni, P. N. Nieto and G Torri:
NMR of Sulfated Oligo- and Polysaccharides.
In: NMR Spectroscopy of Glycoconjugates (J.Jimenez-Barbero and T.Peters, Eds.), Wiley-VCH, Weinheim, 2002, pp. 189-229.
M.Hricovíni, M.Guerrini, A. Bisio, G Torri, M. Petitou and B. Casu:
Conformation of heparin-derived pentasaccharide bound to antithrombin III.
Biochem. J., 359 (2001) 265-272.
M.Hricovíni, M.Guerrini and A. Bisio:
Structure of heparin-derived tetrasaccharide complexed to the plasma protein antithrombin derived from NOEs, J-couplings and chemical shifts.
Eur. J. Biochem., 261 (1999) 789-801.
M.Hricovíni, O.L.Malkina, F.Bízik, L.Turi-Nagy and V.G.Malkin:
Calculation of NMR Chemical Shifts and Spin-Spin Coupling Constants in the Monosaccharide Methyl-i-D-xylopyranoside Using a Density Functional Theory Approach.
J. Phys. Chem. A 101 (1997) 9756-9762.
M.Hricovíni and G.Torri:
Dynamics in Aqueous Solution of the Pentasaccharide Corresponding to the Binding Site of Heparin for Antithrombin III Studied by NMR Relaxation Measurements.
Carbohydr.Res., 268 (1995) 159-175.
M.Hricovíni, R.N.Shah and J.P.Carver:
Detection of Internal Motions in Oligosaccharides by 1H Relaxation Measurements at Different Magnetic Fields.
Biochemistry 31 (1992) 10018-10023.
Institute of Chemistry
Slovak Academy of Sciences
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2017