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Eva MACHOVÁ, PhD
Senior Research Scientist

Microbial Polymers Group

Tel.: +421-2-59410274
Fax.: +421-2-59410222
Research Interests
Fungal polysaccharides - water soluble derivatives, physico-chemical characterization, enzymatic and ultrasonic depolymerization, antioxidant properties. Polysaccharide-protein conjugate as vaccine candidate.
Selected Publications (full list available on request)
Scavenging and antioxidant activities of immunomodulating polysaccharides isolated from Salvia
officinalis L.
Capek, P., Machova, E., Turjan, J.
International journal of biological macromolecules 44, 75-80, 2009
Growth Inhibition of Candida albicans in the Presence of Antiserum Elicited in Rabbits by Mannan-Protein Conjugate.
Machova, E., Bystricky, S.
Zeitschrift fur naturforschung section c-a journal of biosciences 63, 909-912, 2008
Immune responsiveness of a novel peptidoglycan conjugate prepared from surface Candida immunogens: mannan and CR3-related protein.
Paulovicova, E., Bystricky, S., Machova, E., et al.
Fems immunology and medical microbiology 53, 421-428, 2008
Evaluation of different mannan polysaccharide usage in enzyme-linked immunosorbent assay for specific antibodies determination.
Libjakova, L., Bystricky, S., Lizicarova, I., et al.
Journal of pharmaceutical and biomedical analysis 45, 521-525, 2007
Cell and antibody mediated immunity induced by vaccination with novel Candida dubliniensis mannan immunogenic conjugate.
Paulovicova, E., Machova, E., Tulinska, J., et al.
International immunopharmacology 7, 1325-1333, 2007
Human pathogen Candida dubliniensis: A cell wall mannan with a high content of beta-1,2-linked mannose residues.
Lizicarova, I., Matulova, M., Capek, P., et al.
Carbohydrate polymers 70, 89-100, 2007
Carboxymethylated (1 -> 3)-beta-D-glucan protects liposomes against ultraviolet light-induced lipid peroxidation.
Schronerova, K., Babincova, M., Machova, E., et al.
Journal of medicinal food 10, 189-193, 2007
Cell wall mannan of human pathogen Candida dubliniensis.
Lizicarova, I., Matulova, M., Machova, E., et al.
Carbohydrate polymers 68, 191-195, 2007
Antioxidant activity of medicinal plant polysaccharides.
Kardosova, A., Machova, E.
Fitoterapia 77, 367-373, 2006
Immunological properties of complex conjugates based on Vibrio cholerae O1 Ogawa lipopolysaccharide antigen.
Paulovicova, E., Machova, E., Hostacka, A., et al.
Clinical and experimental immunology 144, 521-527, 2006
Synthesis and characterization of new biodegradable hyaluronan alkyl derivatives.
Mlcochova, P., Bystricky, S., Steiner, B., et al.
Biopolymers 82, 74-79, 2006
Immune response to Saccharomyces cerevisiae mannan conjugate in mice.
Paulovicova, E., Bystricky, S., Masarova, J., et al.
International immunopharmacology 5, 1693-1698, 2005
Synthesis and immunogenicity of polysaccharide-protein conjugate composed of galactoglucoxylomannan of Cryptococcus laurentii galactoglucoxylomannan of Cryptococcus laurentii.
Bystricky, S., Paulovicova, E., Machova, E.
Fems microbiology letters 235, 311-314, 2004
Fungal chitin-glucan derivatives exert protective or damaging activity on plasmid DNA.
Kogan, G., Rauko, A., Machova, E.
Carbohydrate research 338, 931-935, 2003
Effect of gluco-monosaccharides and different conditions on digestion of hyaluronan by testicular hyaluronidase.
Bystricky, P., Machova, E., Kolarova, N.
General physiology and biophysics 21, 463-469, 2002
Nonbiodegradable hyaluronan derivative prepared by reaction with a water-soluble carbodiimide.
Bystricky, S., Alfoldi, J., Machova, E., et al.
Chemical papers-chemicke zvesti 55, 49-52, 2001
Polysaccharides in the antipsoriatic mahonia extract: Structure of a (1 -> 4)-beta-D-glucan.
Kardosova, A., Alfoldi, J., Machova, E., et al.
Chemical papers-chemicke zvesti 55, 192-195, 2001
Candida albicans mannan-protein conjugate as vaccine candidate against candidiasis.
S. Bystrický, E. Paulovičová, E. Machová
Immunology Letters 85, 251-255, 2003
Preparation of a subcellular conjugate with the lipopolysaccharide from Vibrio cholerae 01 using β-D-glucan as matrix.
E. Machová, S. Bystrický, A. Gáliková, G. Kogan
Eur. J. Med. Chemistry 37, 681-687, 2002.
Antioxidant properties of carboxymethylglucan: Comparative analysis.
M. Babincová, Z. Bačová, E. Machová, G. Kogan
Journal of Medicinal Food, 5, 79-83, 2002.
Conjugation of yeast mannans with protein employing cyanopyridinium agent (CDAP) - an effective route of antifungal vaccine preparation.
S. Bystrický, E. Machová, P. Bartek, N. Kolarova and G. Kogan
Glycoconjugate Journal 17, 677-680, 2000.
Ultrasonic depolymerization of the chitin-glucan isolated from Aspergillus niger.
E. Machová, G. Kogan, L. Šoltés, K. Kvapilová, J. Šandula
Reactive and Functional Polymers, 43 (2), 265-271, 1999.
Effect of ultrasonic treatment on the molecular weight of carboxymethylated chitin-glucan complex from Aspergillus niger.
E. Machová, K. Kvapilová, G. Kogan, J. Šandula
Ultrasonics Sonochemistry 5, 169-172, 1999.
Enzymatic and ultrasonic depolymerization of carboxymethylated β-1,3-D-glucans derived from Saccharomyces cerevisiae.
E. Machová, G. Kogan, J. Alföldi, L. Šoltés, J. Šandula
Appl. Polym. Sci., 55, 699-704, 1995.
Institute of Chemistry
Slovak Academy of Sciences
webmaster@chem.sk
2016