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JŠn MUCHA, PhD
Senior Research Scientist

Department of Glycobiology

Tel.: +421-2-59410351
Fax: +421-2-59410222
Research Interests
Molecular glycobiology with main research area in molecular cloning, expression and structure - function study of the carbohydrate processing enzymes.
Publications (1999-2004)
Mucha J, Domlatil J, Lochnit G, Rendic D, Paschinger K, Hinterkorner G, Hofinger A, Kosma P, Wilson IB.
The Drosophila melanogaster homologue of the human histo-blood group Pk gene encodes a glycolipid-modifying alpha1,4-N-acetylgalactosaminyltransferase.
Biochem J. (2004) 15, 382:67-74
R.Griessler, A. Schwarz, J.Mucha, B. Nidetzky
Tracking interactions that stabilize the dimer structure of starch phosphorylase from Corynebacterium callunae. Roles of Arg234 and Arg242 revealed by sequence analysis and site-directed mutagenesis. Eur J Biochem. (2003)270,10:2126-36.
T. Peterbauer, U. Karner, J. Mucha, L. Mach, D. A. Jones, C. L. Hedley and A. Richter
Enzymatic control of the accumulation of verbascose in pea seeds
Plant, Cell and Environment (2003)26, 1385-1391
J.Mucha, B. Svoboda, S. Kappel, R. Strasser, P. Bencur, U. Frohwein, H. Schachter, L. Mach and J. Glossl
Two closely related forms of UDP-GlcNAc: alfa 6-D-mannoside beta 1,2-N-acetylglucosaminyltransferase II occur in the clawed frog X. laevis
Glycoconj. J. (2003), 19, 187-195
T.Peterbauer, L. Mach, J. Mucha, A. Richter
Functional expression of a cDNA encoding pea (Pisum sativum L.) raffinose synthase, partial purification of the enzyme from maturing seeds, and steady-state kinetic analysis of raffinose synthesis.
Planta. (2002)215(5):839-46
T. Peterbauer, J. Mucha, L. Mach, A. Richter
Chain Elongation of raffinose in pea seeds. Isolation, characterization, and molecular cloning of mutifunctional enzyme catalyzing the synthesis of stachyose and verbascose.
J Biol Chem. (2002) 4;277(1):194-200.
T. Peterbauer, L.B. Lahuta, A. Blochl, J. Mucha, D.A. Jones, C.L.Hedley, R.J. Gorecki, A. Richter
Analysis of the raffinose family oligosaccharide pathway in pea seeds with contrasting carbohydrate composition.
Plant Physiol. (2001)127(4):1764-72.
J. Mucha, B. Svoboda, U. Frohwein, R. Strasser, m. Mischinger, H. Schwihla, F. Altmann, W. Hane, H. Schachter, J. Gloessl, L. Mach
Tissues of the clawed frog Xenopus laevis contain two closely related forms of UDP-GlcNAc:alpha3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.
Glycobiology. (2001)11(9):769-78
C. Breton, J. Mucha, C. Jeanneau
Structural and functional features of glycosyltransferases.
Biochimie. (2001)83(8):713-8. Review.
I.B. Wilson, D. Rendic, A. Freilinger, J. Dumic, F. Altmann, J. Mucha, S. Muller, M.T. Hauser
Cloning and expression of cDNAs encoding alpha1,3-fucosyltransferase homologues from Arabidopsis thaliana.
Biochim Biophys Acta. (2001)1527(1-2):88-96
R. Strasser, J. Mucha, L. Mach, F. Altmann, I.B. Wilson, J. Gloessl, H. Steinkellner
Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana.
FEBS Lett. (2000)472(1):105-8.
H. Leiter, J. Mucha, E. Staudacher, R. Grimm, J. Gloessl, F. Altmann
Purification, cDNA cloning, and expression of GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase from mung beans.
J Biol Chem. (1999)274(31):21830-9.
Institute of Chemistry
Slovak Academy of Sciences
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2017